4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Base Information

Chemical Name:4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline
CAS No.:101697-25-0
Molecular Formula:C₁₆H₁₅F₁₂NO₂
Molecular Weight:481.281
Hs Code.:

Synonyms:4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Suppliers and Price of 4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

There total 3 articles about 4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6-bromo-4-tert-butyl-2-<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

: 101697-25-0
4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent

2: 44 percent / n-BuLi / diethyl ether; tetrahydrofuran

3: 22 g / H⁽¹⁺⁾

With n-butyllithium; hydrogen cation; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja00273a041

Reference yield:

: 101697-23-8
1,4-dihydro-8-bromo-6-tert-butyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine

: 101697-25-0
4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / n-BuLi / diethyl ether; tetrahydrofuran

2: 22 g / H⁽¹⁺⁾

With n-butyllithium; hydrogen cation; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja00273a041