(R)-α-chlorobenzeneacetic acid benzyl ester

Base Information

• Chemical Name: (R)-α-chlorobenzeneacetic acid benzyl ester
• CAS No.: 1357467-73-2
• Molecular Formula: C₁₅H₁₃ClO₂
• Molecular Weight: 260.72
• Mol file: 1357467-73-2.mol

Synonyms:(R)-α-chlorobenzeneacetic acid benzyl ester

Chemical Property of (R)-α-chlorobenzeneacetic acid benzyl ester

Chemical Property:

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Technology Process of (R)-α-chlorobenzeneacetic acid benzyl ester

There total 1 articles about (R)-α-chlorobenzeneacetic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(S)-benzyl 2-hydroxy-2-phenylacetate (62173-99-3) → (R)-α-chlorobenzeneacetic acid benzyl ester (1357467-73-2)

Guidance literature:

With oxalyl dichloride; 2,3-bis(4-methoxyphenyl)cyclopropenone; In 4-methyl-1,2,3-trifluorobenzene; at 80 ℃; for 4h; Inert atmosphere;

DOI:10.1002/anie.201104638

upstream raw materials:

(S)-benzyl 2-hydroxy-2-phenylacetate