(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Base Information

Chemical Name:(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate
CAS No.:1620908-09-9
Molecular Formula:C₃₉H₅₆O₆
Molecular Weight:620.87
Hs Code.:

Synonyms:(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Suppliers and Price of (22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Chemical Property:

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Technology Process of (22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

There total 8 articles about (22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1214998-94-3
(22β,25R)-3β-acetoxyfurost-5,6-dehydro-26-al

: 61240-20-8
triphenyl-(3,4,5-trimethoxybenzyl)phosphonium bromide

: 1620908-09-9
(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Guidance literature:: triphenyl-(3,4,5-trimethoxybenzyl)phosphonium bromide; With sodium hydride; In toluene; for 0.333333h; Reflux;

(22β,25R)-3β-acetoxyfurost-5,6-dehydro-26-al; In toluene; for 4h; Reflux;
DOI:10.1016/j.jsbmb.2014.04.006

Reference yield: 29.0%

: (22β,25R)-3β-hydroxy-26-formyl-furost-5-en 3-O-acetate

: 61240-20-8
triphenyl-(3,4,5-trimethoxybenzyl)phosphonium bromide

: 1620908-08-8
(22β)-(Z)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

: 1620908-09-9
(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Guidance literature:: triphenyl-(3,4,5-trimethoxybenzyl)phosphonium bromide; With sodium hydride; In toluene; mineral oil; for 0.333333h;

(22β,25R)-3β-hydroxy-26-formyl-furost-5-en 3-O-acetate; In toluene; mineral oil;
DOI:10.1016/j.steroids.2014.05.025

Reference yield:

: 512-04-9
diosgenin

: 1620908-09-9
(22β)-(E)-26-(3,4,5-trimethoxybenzylidene)-3β-hydroxy-furost-5-en 3-O-acetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine / chloroform / 2 h / 20 °C

2.1: acetic acid; sodium cyanoborohydride / 3 h / 20 °C

3.1: pyridinium chlorochromate / dichloromethane / 1 h / Reflux

4.1: sodium hydride / toluene / 0.33 h / Reflux

4.2: 4 h / Reflux

With pyridine; sodium hydride; sodium cyanoborohydride; acetic acid; pyridinium chlorochromate; In dichloromethane; chloroform; toluene; 4.1: |Wittig Olefination / 4.2: |Wittig Olefination;
DOI:10.1016/j.jsbmb.2014.04.006