(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

Base Information

Chemical Name:(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone
CAS No.:167824-16-0
Molecular Formula:C₃₇H₃₈N₂O₆
Molecular Weight:606.719
Hs Code.:

Synonyms:(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

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Chemical Property of (4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

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Technology Process of (4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

There total 3 articles about (4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₉H₄₀N₂O₇

: 167824-16-0
(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

Guidance literature:: With sodium hydroxide; In methanol; Ambient temperature;
DOI:10.1021/jm970081i

Reference yield:

: C₃₇H₃₈N₂O₇

: 167824-16-0
(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 0.25 h / Ambient temperature

2: Zn (dust), AcOH / Ambient temperature

3: 1 N aq. NaOH / methanol / Ambient temperature

With sodium hydroxide; acetic acid; zinc; In methanol; dichloromethane;
DOI:10.1021/jm970081i

Reference yield:

: C₃₉H₃₉BrN₂O₇

: 167824-16-0
(4R,5R,6R)-tetrahydro-1,3-bis[(3-carbomethoxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone

Guidance literature:: Multi-step reaction with 2 steps

1: Zn (dust), AcOH / Ambient temperature

2: 1 N aq. NaOH / methanol / Ambient temperature

With sodium hydroxide; acetic acid; zinc; In methanol;
DOI:10.1021/jm970081i