Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine

Base Information

• Chemical Name: Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine
• CAS No.: 83676-27-1
• Molecular Formula: C₁₄H₉ClN₂O
• Molecular Weight: 256.691
• Mol file: 83676-27-1.mol

Synonyms:Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine

Chemical Property of Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine

There total 3 articles about Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1,3-benzoxazol-2-amine (4570-41-6) + 4-chlorobenzaldehyde (104-88-1) → Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine (83676-27-1)

Guidance literature:

With piperidine; In ethanol; for 3h; Heating;

Reference yield:

benzoxazole (273-53-0,29791-96-6) → Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine (83676-27-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₂OH*HCl, 1N NaOH

2: 55 percent / piperidine / ethanol / 3 h / Heating

With piperidine; sodium hydroxide; hydroxylamine hydrochloride; In ethanol;

Reference yield:

2-hydroxylamino-2,3-dihydrobenzoxazole (83676-46-4) → Benzooxazol-2-yl-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine (83676-27-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.08 h / 180 - 200 °C

2: 55 percent / piperidine / ethanol / 3 h / Heating

With piperidine; In ethanol;

upstream raw materials:

1,3-benzoxazol-2-amine

4-chlorobenzaldehyde

benzoxazole

2-hydroxylamino-2,3-dihydrobenzoxazole

Downstream raw materials:

N-(benzo[d]oxazol-2-yl)-4-chlorobenzamide