2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-penten-1-yl]-2,3-dimethoxy-

Base Information

• Chemical Name: 2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-penten-1-yl]-2,3-dimethoxy-
• CAS No.: 118297-32-8
• Molecular Formula: C18H20 O5
• Molecular Weight: 316.354
• Mol file: 118297-32-8.mol

Synonyms:2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-pentenyl]-2,3-dimethoxy- (9CI);2,5-Cyclohexadiene-1,4-dione,5-[5-(3-furanyl)-2-methyl-2-pentenyl]-2,3-dimethoxy-, (E)-; Isoarnebifuranone

Chemical Property of 2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-penten-1-yl]-2,3-dimethoxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-penten-1-yl]-2,3-dimethoxy-

There total 5 articles about 2,5-Cyclohexadiene-1,4-dione,5-[(2E)-5-(3-furanyl)-2-methyl-2-penten-1-yl]-2,3-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(E)-4-<7-(3-Furanyl)-4-methyl-4-hepten-1-ynyl>-2,3-dimethoxy-4-hydroxy-2-cyclobuten-1-one (118172-09-1) → (E)-6-[5-(3-furyl)-2-methylpent-2-enyl]-2,3-dimethoxy-1,4-benzoquinone (118297-32-8)

Guidance literature:

In various solvent(s); for 0.333333h; Heating;

DOI:10.1021/ja00185a031

Reference yield:

2-(3-furyl)-1-bromoethane (98126-46-6) → (E)-6-[5-(3-furyl)-2-methylpent-2-enyl]-2,3-dimethoxy-1,4-benzoquinone (118297-32-8)

Guidance literature:

Multi-step reaction with 4 steps

1: Dilithium tetrachlorocuprate / THF; 1.) 38-40 deg C, 30 min; 2.) 38-42 deg C, 5.25 h

2: 89 percent / aq. AgNO₃, aq. KCN / ethanol / 25 h / Ambient temperature

3: 1.) n-BuLi / THF, -78 deg C; 1. 45 min; 2. 30 min

4: 86 percent / various solvent(s) / 0.33 h / Heating

With potassium cyanide; n-butyllithium; silver nitrate; dilithium tetrachlorocuprate; In ethanol;

DOI:10.1021/ja00185a031

Reference yield:

(E)-3-(4-Methyl-3-hepten-6-ynyl)furan (118172-08-0) → (E)-6-[5-(3-furyl)-2-methylpent-2-enyl]-2,3-dimethoxy-1,4-benzoquinone (118297-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) n-BuLi / THF, -78 deg C; 1. 45 min; 2. 30 min

2: 86 percent / various solvent(s) / 0.33 h / Heating

With n-butyllithium; In various solvent(s);

DOI:10.1021/ja00185a031

upstream raw materials:

(E)-4-<7-(3-Furanyl)-4-methyl-4-hepten-1-ynyl>-2,3-dimethoxy-4-hydroxy-2-cyclobuten-1-one

3-[3-(2,3-dimethoxyphenoxy)-4-methylpent-4-enyl]furan

2-(3-furyl)-1-bromoethane

(E)-3-(4-Methyl-3-hepten-6-ynyl)furan