(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

Base Information

Chemical Name:(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile
CAS No.:205646-85-1
Molecular Formula:C₂₀H₁₅Cl₂N₃O₂
Molecular Weight:400.264
Hs Code.:

Synonyms:(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

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Chemical Property of (E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

Chemical Property:

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Technology Process of (E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

There total 1 articles about (E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 205646-84-0
ethyl (Z)-4,6-dichloro-3-[2-cyano-2-(3-nitrophenyl)-ethenyl]-1H-indole-2-carboxylate

: 205646-48-6
(E)-2-(3-nitrophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

: 205646-85-1
(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

: 205646-86-2
ethyl (Z)-4,6-dichloro-3-[2-(3-aminophenyl)2-cyanoethenyl]-1H-indole-2-carboxylate

Guidance literature:: ethyl (Z)-4,6-dichloro-3-[2-cyano-2-(3-nitrophenyl)-ethenyl]-1H-indole-2-carboxylate; (E)-2-(3-nitrophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile; With water; tin(ll) chloride; In ethyl acetate; for 3h; Heating / reflux;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 205646-85-1
(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile

: 205646-86-2
ethyl (Z)-4,6-dichloro-3-[2-(3-aminophenyl)2-cyanoethenyl]-1H-indole-2-carboxylate

: 1099474-23-3
(E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenoic acid amide

: 1099474-22-2
ethyl (Z)-4,6-dichloro-3-[(3-amino-2-aminophenyl)-3-oxo-1-propenyl]-1H-indole-2-carboxylate

Guidance literature:: (E)-2-(3-aminophenyl)-3-(2-carboethoxy-4,6-dichloroindol-3-yl)-propenonitrile; ethyl (Z)-4,6-dichloro-3-[2-(3-aminophenyl)2-cyanoethenyl]-1H-indole-2-carboxylate; With sulfuric acid; water; acetic acid; at 90 ℃; for 2h;

With sodium hydroxide; In water; pH=5;