2,3-Dichloro-6,7-difluoroquinoxaline

Base Information

• Chemical Name: 2,3-Dichloro-6,7-difluoroquinoxaline
• CAS No.: 91895-30-6
• Molecular Formula: C₈H₂Cl₂F₂N₂
• Molecular Weight: 235.02
• DSSTox Substance ID: DTXSID20443450
• Wikidata: Q82261282
• Mol file: 91895-30-6.mol

Synonyms:2,3-DICHLORO-6,7-DIFLUOROQUINOXALINE;91895-30-6;Quinoxaline, 2,3-dichloro-6,7-difluoro-;SCHEMBL121641;DTXSID20443450;CMQLMJCICYOHDE-UHFFFAOYSA-N;MFCD18533623;6,7-difluoro-2,3-dichloroquinoxaline;DS-12241;CS-0170893;A916316

Chemical Property of 2,3-Dichloro-6,7-difluoroquinoxaline

Chemical Property:

• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 233.9563098
• Heavy Atom Count: 14
• Complexity: 198

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dichloro-6,7-difluoroquinoxaline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C2C(=CC(=C1F)F)N=C(C(=N2)Cl)Cl

Technology Process of 2,3-Dichloro-6,7-difluoroquinoxaline

There total 4 articles about 2,3-Dichloro-6,7-difluoroquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6,7-difluoro-1,4-dihydro-2,3-quinoxalinedione (91895-29-3) → 2,3-dichloro-6,7-difluoroquinoxaline (91895-30-6)

Guidance literature:

With trichlorophosphate; for 16h; Heating;

DOI:10.1021/jm00170a031

Reference yield: 60.0%

→ 2,3-dichloro-6,7-difluoroquinoxaline (91895-30-6)

Guidance literature:

Reference yield:

2-amino-4,5-difluoroaniline (76179-40-3) → 2,3-dichloro-6,7-difluoroquinoxaline (91895-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 24 h / Heating

2: POCl₃ / 16 h / Heating

With trichlorophosphate;

DOI:10.1016/S0223-5234(99)80019-1

upstream raw materials:

6,7-difluoro-1,4-dihydro-2,3-quinoxalinedione

2,3-dihydroxy-6,7-difluoroquinoxaline

2-amino-4,5-difluoroaniline