(R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate

Base Information

• Chemical Name: (R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate
• CAS No.: 957266-68-1
• Molecular Formula: C₂₇H₂₉NO₁₀S
• Molecular Weight: 559.594
• Mol file: 957266-68-1.mol

Synonyms:(R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate

Chemical Property of (R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate

There total 1 articles about (R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(R)-2-hydroxy-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)propyl benzoate (957266-67-0) + p-toluenesulfonyl chloride (98-59-9) → (R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate (957266-68-1)

Guidance literature:

With dmap; In dichloromethane; at 35 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2008.09.025

Reference yield:

(R)-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)-2-(tosyloxy)propyl benzoate (957266-68-1) → C27H31NO8S

Guidance literature:

With 10% Pd/C; hydrogen; potassium carbonate; In tetrahydrofuran; for 48h; Inert atmosphere;

DOI:10.1016/j.bmc.2008.09.025

upstream raw materials:

(R)-2-hydroxy-3-(5-((2-methoxyethoxy)methoxy)-2-nitrophenyl)propyl benzoate

p-toluenesulfonyl chloride