C₂₂H₂₂⁽¹⁸⁾FN₃O

Base Information

• Chemical Name: C₂₂H₂₂⁽¹⁸⁾FN₃O
• CAS No.: 1314081-23-6
• Molecular Formula: C₂₂H₂₂FN₃O
• Molecular Weight: 362.436
• Mol file: 1314081-23-6.mol

Synonyms:C₂₂H₂₂⁽¹⁸⁾FN₃O

Chemical Property of C₂₂H₂₂⁽¹⁸⁾FN₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₂⁽¹⁸⁾FN₃O

There total 4 articles about C₂₂H₂₂⁽¹⁸⁾FN₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C32H38(18)FN3O5 (1314081-22-5) → C22H22(18)FN3O (1314081-23-6)

Guidance literature:

With hydrogenchloride; In ethyl acetate;

Reference yield:

di-tert-butyl {6-[4-(2-hydroxyethoxy)phenyl]phenanthridine-3,8-diyl}dicarbamate → C22H22(18)FN3O (1314081-23-6)

Guidance literature:

Multi-step reaction with 5 steps

1: toluene / 70 °C

2: sodium tetrahydroborate / methanol / 0.17 h / 0 °C

3: triethylamine / dichloromethane / 2 h / 0 °C

4: [¹⁸F]-potassium fluoride; [2.2.2]cryptande / acetonitrile; dimethyl sulfoxide / 0.17 h / 100 °C

5: hydrogenchloride; water / ethyl acetate / 0.17 h / 100 °C

With hydrogenchloride; sodium tetrahydroborate; [¹⁸F]-potassium fluoride; water; triethylamine; [2.2.2]cryptande; In methanol; dichloromethane; dimethyl sulfoxide; ethyl acetate; toluene; acetonitrile;

DOI:10.1021/acschemneuro.7b00385

Reference yield:

C32H39N3O6 → C22H22(18)FN3O (1314081-23-6)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 2 h / 0 °C

2: [¹⁸F]-potassium fluoride; [2.2.2]cryptande / acetonitrile; dimethyl sulfoxide / 0.17 h / 100 °C

3: hydrogenchloride; water / ethyl acetate / 0.17 h / 100 °C

With hydrogenchloride; [¹⁸F]-potassium fluoride; water; triethylamine; [2.2.2]cryptande; In dichloromethane; dimethyl sulfoxide; ethyl acetate; acetonitrile;

DOI:10.1021/acschemneuro.7b00385

upstream raw materials:

C₃₂H₃₈⁽¹⁸⁾FN₃O₅