Pyridoxal 5'-phosphate

Base Information

• Chemical Name: Pyridoxal 5'-phosphate
• CAS No.: 41468-25-1
• Molecular Formula: C8H12NO7P
• Molecular Weight: 265.15
• Hs Code.: 2936250000
• UNII: 5V5IOJ8338
• DSSTox Substance ID: DTXSID7046594
• Wikidata: Q27888204
• NCI Thesaurus Code: C81627
• ChEMBL ID: CHEMBL3181870
• Mol file: 41468-25-1.mol

Synonyms:3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde monohydrate;3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate monohydrate;Phosphopyridoxal monohydrate;Pyridoxal-5-monophosphoric acid ester monohydrate;UNII-5V5IOJ8338;

Chemical Property of Pyridoxal 5'-phosphate

Chemical Property:

• Appearance/Colour: pale yellowish white crystalline powder
• Vapor Pressure: 1.23E-13mmHg at 25°C
• Melting Point: 140-143 °C(lit.)
• Boiling Point: 565.7 °C at 760 mmHg
• Flash Point: 296 °C
• PSA: 135.99000
• LogP: 0.45310
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive
• Solubility.: Acetonitrile (Slightly), DMSO (Slightly)
• Water Solubility.: 5 g/L (20 ºC)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 265.03513872
• Heavy Atom Count: 17
• Complexity: 292

Purity/Quality:

99% ^*data from raw suppliers

PLP1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O
• Recent EU Clinical Trials: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER
• Uses: Pyridoxal 5-phosphate (PLP) (active form of Vitamin B6) is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.