2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Base Information

Chemical Name:2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide
CAS No.:266338-89-0
Molecular Formula:C₂₉H₄₇N₅O₆
Molecular Weight:561.722
Hs Code.:

2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Synonyms:2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

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Chemical Property of 2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

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Technology Process of 2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

There total 8 articles about 2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 54856-83-6
3-dimethylamino-2,2-dimethyl-2H-azirine

: 266338-85-6
2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methylpropanoic acid

: 266338-89-0
2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Guidance literature:: In acetonitrile; at 20 ℃; for 25h;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<233::AID-HLCA233>3.0.CO;2-1

Reference yield:

: 4835-90-9
3-Hydroxy-2,2-dimethylpropanoic acid

: 266338-89-0
2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Guidance literature:: Multi-step reaction with 7 steps

1: 97 percent / acetonitrile / 30 h / 20 °C

2: 95 percent / aq. HCl / tetrahydrofuran / 26 h / 20 °C

3: 87 percent / acetonitrile / 2 h / 20 °C

4: 1.178 g / aq. HCl / tetrahydrofuran / 2 h / 20 °C

5: 66 percent / acetonitrile / 49 h / 20 °C

6: 93 percent / aq. HCl / tetrahydrofuran / 6 h / 20 °C

7: 96 percent / acetonitrile / 25 h / 20 °C

With hydrogenchloride; In tetrahydrofuran; acetonitrile; 1: Addition / 2: Hydrolysis / 3: Addition / 4: Hydrolysis / 5: Addition / 6: Hydrolysis / 7: Addition;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<233::AID-HLCA233>3.0.CO;2-1

Reference yield:

: 114234-21-8
2-benzyl-3-(dimethylamino)-2-methyl-2H-azirine

: 266338-89-0
2-[(2-{[2-({2-benzyl-2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}-2-methyl-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Guidance literature:: Multi-step reaction with 7 steps

1: 97 percent / acetonitrile / 30 h / 20 °C

2: 95 percent / aq. HCl / tetrahydrofuran / 26 h / 20 °C

3: 87 percent / acetonitrile / 2 h / 20 °C

4: 1.178 g / aq. HCl / tetrahydrofuran / 2 h / 20 °C

5: 66 percent / acetonitrile / 49 h / 20 °C

6: 93 percent / aq. HCl / tetrahydrofuran / 6 h / 20 °C

7: 96 percent / acetonitrile / 25 h / 20 °C

With hydrogenchloride; In tetrahydrofuran; acetonitrile; 1: Addition / 2: Hydrolysis / 3: Addition / 4: Hydrolysis / 5: Addition / 6: Hydrolysis / 7: Addition;
DOI:10.1002/(SICI)1522-2675(20000119)83:1<233::AID-HLCA233>3.0.CO;2-1