C₁₉H₁₉F₃N₂O₃

Base Information

Chemical Name:C₁₉H₁₉F₃N₂O₃
CAS No.:1351865-00-3
Molecular Formula:C₁₉H₁₉F₃N₂O₃
Molecular Weight:380.367
Hs Code.:

C<sub>19</sub>H<sub>19</sub>F<sub>3</sub>N<sub>2</sub>O<sub>3</sub>

Synonyms:C₁₉H₁₉F₃N₂O₃

Suppliers and Price of C₁₉H₁₉F₃N₂O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₉H₁₉F₃N₂O₃

Chemical Property:

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Technology Process of C₁₉H₁₉F₃N₂O₃

There total 8 articles about C₁₉H₁₉F₃N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1351864-99-7
C₂₀H₂₁F₃N₂O₃

: 1351865-00-3
C₁₉H₁₉F₃N₂O₃

Guidance literature:: C₂₀H₂₁F₃N₂O₃; With lithium hydroxide; In tetrahydrofuran; water; for 1h;

With hydrogenchloride; In water;

Reference yield:

: 1224883-92-4
1-(4-trifluoromethylphenyl)-5-hexen-1-one

: 1351865-00-3
C₁₉H₁₉F₃N₂O₃

Guidance literature:: Multi-step reaction with 6 steps

1: triethylammonium formate / (S,S)-teth-TsDpen ruthenium chloride / 18 h / 70 °C / Inert atmosphere

2: sodium hydrogencarbonate; iodine / acetonitrile / 1 h / 20 °C

3: N,N-dimethyl-formamide / 18 h / 90 °C

4: ethanolamine / toluene / 3 h / 70 °C

5: caesium carbonate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / toluene; 1,4-dioxane / 110 °C / Inert atmosphere

6: lithium hydroxide / water; tetrahydrofuran / 1 h

With iodine; triethylammonium formate; sodium hydrogencarbonate; caesium carbonate; ethanolamine; lithium hydroxide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 1312590-07-0
C₁₃H₁₅F₃O

: 1351865-00-3
C₁₉H₁₉F₃N₂O₃

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydrogencarbonate; iodine / acetonitrile / 1 h / 20 °C

2: N,N-dimethyl-formamide / 18 h / 90 °C

3: ethanolamine / toluene / 3 h / 70 °C

4: caesium carbonate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / toluene; 1,4-dioxane / 110 °C / Inert atmosphere

5: lithium hydroxide / water; tetrahydrofuran / 1 h

With iodine; sodium hydrogencarbonate; caesium carbonate; ethanolamine; lithium hydroxide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; toluene; acetonitrile;