4-Fluoro-N2-isopropylbenzene-1,2-diamine

Base Information

Chemical Name:4-Fluoro-N2-isopropylbenzene-1,2-diamine
CAS No.:1026934-69-9
Molecular Formula:C₉H₁₃FN₂
Molecular Weight:168.214
Hs Code.:
European Community (EC) Number:970-661-6

Synonyms:1026934-69-9;4-Fluoro-N2-isopropylbenzene-1,2-diamine;5-Fluoro-1-N-isopropylbenzene-1,2-diamine;4-fluoro-2-N-propan-2-ylbenzene-1,2-diamine;5-fluoro-1-N-(propan-2-yl)benzene-1,2-diamine;5-Fluoro-N1-isopropylbenzene-1,2-diamine;SCHEMBL11901396;KVWKNKQHTOSTMO-UHFFFAOYSA-N;BRB93469;AKOS011662385;EN300-62567;5-fluoro-N1-(propan-2-yl)benzene-1,2-diamine

Suppliers and Price of 4-Fluoro-N2-isopropylbenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Fluoro-N2-isopropylbenzene-1,2-diamine

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:168.10627659
Heavy Atom Count:12
Complexity:139

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)NC1=C(C=CC(=C1)F)N

Technology Process of 4-Fluoro-N2-isopropylbenzene-1,2-diamine

There total 2 articles about 4-Fluoro-N2-isopropylbenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131885-33-1
(5-fluoro-2-nitrophenyl)isopropylamine

: 1026934-69-9
5-fluoro-N¹-isopropylbenzene-1,2-diamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 4h; Ambient temperature;
DOI:10.1021/jm960070+

Reference yield:

: 700-36-7
2-bromo-4-fluoronitrobenzene

: 1026934-69-9
5-fluoro-N¹-isopropylbenzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 36 h / 150 °C

2: H₂ / 5percent Pd/C / ethanol / 4 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm960070+

Reference yield:

: 1026934-69-9
5-fluoro-N¹-isopropylbenzene-1,2-diamine

: 7-Fluoro-5-isopropyl-3-phenyl-5H-imidazo[1,5-a]quinoxalin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: EtNiPr₂ / toluene / 1.) from -78 deg C to RT, 16 h, 2.) reflux, 24 h

2: 1.) KOtBu / 1.) THF, from -20 deg C to 0 deg C, 45 min, 2.) THF, from -40 deg C to RT, 30 min

3: KOtBu / tetrahydrofuran / 3 h / -78 - 20 °C

With potassium tert-butylate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; toluene;
DOI:10.1021/jm960070+