(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Base Information

Chemical Name:(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride
CAS No.:128684-20-8
Molecular Formula:C₃₈H₅₄N₆O₆*ClH
Molecular Weight:727.344
Hs Code.:

(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Synonyms:(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Suppliers and Price of (R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

There total 12 articles about (R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34985-37-0
(S)-2-methylbutylamine

: 128684-20-8
(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1: 95 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), 4-(dimethylamino)pyridine / dimethylformamide

2: HCl, AcOH

3: 60 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

4: 96 percent / H₂, ammonium formate / 10percent Pd-C / ethanol; H₂O / 0.25 h

5: 36 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

6: 4N aq. NaOH / methanol

7: 3N HCl, AcOH

With hydrogenchloride; dmap; sodium hydroxide; hydrogen; ammonium formate; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00171a034

Reference yield:

: 2389-45-9
Boc-Lys(Z)-OH

: 128684-20-8
(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

2: 96 percent / H₂, ammonium formate / 10percent Pd-C / ethanol; H₂O / 0.25 h

3: 36 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

4: 4N aq. NaOH / methanol

5: 3N HCl, AcOH

With hydrogenchloride; sodium hydroxide; hydrogen; ammonium formate; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00171a034

Reference yield:

: 128684-37-7
Boc-D-Trp(S)-(-)-2-methylbutylamide

: 128684-20-8
(R)-2-(4-{(S)-5-Amino-5-[(R)-2-(1H-indol-3-yl)-1-((S)-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-4-methyl-pentanoylamino)-3-phenyl-propionic acid; hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: HCl, AcOH

2: 60 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

3: 96 percent / H₂, ammonium formate / 10percent Pd-C / ethanol; H₂O / 0.25 h

4: 36 percent / dicyclohexylcarbodiimide (DCCI), 1-hydroxybenzotriazole (HOBt), triethylamine / dimethylformamide

5: 4N aq. NaOH / methanol

6: 3N HCl, AcOH

With hydrogenchloride; sodium hydroxide; hydrogen; ammonium formate; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00171a034