cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

Base Information

Chemical Name:cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
CAS No.:291306-32-6
Molecular Formula:C₂₂H₂₄Cl₂N₄O
Molecular Weight:431.365
Hs Code.:

Synonyms:cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

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Chemical Property of cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

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Technology Process of cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

There total 1 articles about cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(1-ethoxymethyl)-1H-1,2,4-triazole

: 291306-20-2
(1S-cis )-4-(3,4-dichlorophenyl)-7-iodo-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine

: 291306-32-6
cis-(1S)-N-methyl-7-(3-((2-ethoxymethyl)-1,2,4-triazolyl))-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

Guidance literature:: 1-(1-ethoxymethyl)-1H-1,2,4-triazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h;

With zinc(II) chloride; In tetrahydrofuran; hexane; for 0.333333h;

(1S-cis )-4-(3,4-dichlorophenyl)-7-iodo-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; hexane; at 20 ℃; for 16h; Heating / reflux;