1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime

Base Information

• Chemical Name: 1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime
• CAS No.: 154874-68-7
• Molecular Formula: C₁₀H₁₉NO₂
• Molecular Weight: 185.266
• Mol file: 154874-68-7.mol

Synonyms:1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime;Ethanone, 1-(1-hydroxycyclohexyl)-, O-ethyloxime;154874-68-7;1-[(Z)-N-ethoxy-C-methylcarbonimidoyl]cyclohexan-1-ol;LS-67455

Chemical Property of 1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime

Chemical Property:

• Vapor Pressure: 0.000753mmHg at 25°C
• Boiling Point: 273.1°Cat760mmHg
• PKA: 13.85±0.20(Predicted)
• Flash Point: 119°C
• PSA: 41.82000
• Density: 1.04g/cm³
• LogP: 2.09400
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 185.141578849
• Heavy Atom Count: 13
• Complexity: 183

Purity/Quality:

ETHANONE, 1-(1-HYDROXYCYCLOHEXYL)-, O-ETHYLOXIME 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCON=C(C)C1(CCCCC1)O
• Isomeric SMILES: CCO/N=C(/C)\C1(CCCCC1)O

Technology Process of 1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime

There total 2 articles about 1-(1-Hydroxycyclohexyl)ethanone O-ethyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1-(1-hydroxycyclohexyl)ethan-1-one (1123-27-9) + O-ethylhydroxylamine hydrochloride (3332-29-4) → 1-(1-Hydroxy-cyclohexyl)-ethanone O-ethyl-oxime (154874-68-7)

Guidance literature:

With sodium acetate; In ethanol; for 20h; Heating;

DOI:10.1016/0223-5234(93)90044-F

Reference yield:

1-Ethynylcyclohexan-1-ol (78-27-3) → 1-(1-Hydroxy-cyclohexyl)-ethanone O-ethyl-oxime (154874-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O, H₂SO₄

2: 25 percent / sodium acetate / ethanol / 20 h / Heating

With sulfuric acid; water; sodium acetate; In ethanol;

DOI:10.1016/0223-5234(93)90044-F

upstream raw materials:

1-(1-hydroxycyclohexyl)ethan-1-one

O-ethylhydroxylamine hydrochloride

1-Ethynylcyclohexan-1-ol

Refernces