dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate

Base Information

• Chemical Name: dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate
• CAS No.: 166953-83-9
• Molecular Formula: C₁₄H₁₅BrO₇
• Molecular Weight: 375.173
• Mol file: 166953-83-9.mol

Synonyms:dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate

Chemical Property of dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate

There total 2 articles about dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

dimethyl 2,2'-(4-acetyl-1,3-phenylene)bis(oxy)diacetate (166953-85-1) → dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate (166953-83-9)

Guidance literature:

With copper(I) bromide; In chloroform; ethyl acetate; for 0.333333h; Sonication;

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate (166953-83-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; potassium iodide / acetonitrile / 26 h / Reflux

2: copper(ll) bromide / chloroform; ethyl acetate / 0.33 h / Sonication

With potassium carbonate; potassium iodide; copper(ll) bromide; In chloroform; ethyl acetate; acetonitrile;

DOI:10.2174/15734064113096660070

Reference yield: 86.0%

PHTHALAZINE (253-52-1) + dimethyl 2,2'-(4-(2-bromoacetyl)-1,3-phenylene)bis(oxy)diacetate (166953-83-9) → 2-(2-(2,4-Bis(2-methoxy-2-oxoethoxy)phenyl)-2-oxoethyl)phthalazin-2-ium bromide (1527500-99-7)

Guidance literature:

In acetone; for 0.25h; Sonication;

DOI:10.2174/15734064113096660070

upstream raw materials:

dimethyl 2,2'-(4-acetyl-1,3-phenylene)bis(oxy)diacetate

2',4'-dihydroxy-4-acetophenone

Downstream raw materials:

1-(2-(2,4-Bis(2-methoxy-2-oxoethoxy)phenyl)-2-oxoethyl)pyridazin-1-ium bromide

2-(2-(2,4-Bis(2-methoxy-2-oxoethoxy)phenyl)-2-oxoethyl)phthalazin-2-ium bromide