5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole

Base Information

• Chemical Name: 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole
• CAS No.: 97583-93-2
• Molecular Formula: C₂₄H₁₉N₃O₄
• Molecular Weight: 413.433
• Mol file: 97583-93-2.mol

Synonyms:5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole

Chemical Property of 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole

There total 4 articles about 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

acetic anhydride (108-24-7) + 2-amino-4-phenyl-5-acetyl-3-cyano-4H-pyrano<3,2-b>indole (97583-87-4) → 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole (97583-93-2)

Guidance literature:

With potassium acetate; for 0.5h; Heating;

DOI:10.1007/BF00504208

Reference yield:

1-acetyl-2,3-dihydro-1H-indol-3-one (16800-68-3) → 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole (97583-93-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / piperidine / 3.5 h / Heating

2: 70 percent / C₂H₅ONa / dimethylformamide / 1 h / Heating

3: 85 percent / CH₃CO₂K / 0.5 h / Heating

With piperidine; sodium ethanolate; potassium acetate; In N,N-dimethyl-formamide;

DOI:10.1007/BF00504208

Reference yield:

1-acetyl-2-benzylideneindolin-3-one (95542-12-4) → 5-acetyl-2-diacetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole (97583-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / C₂H₅ONa / dimethylformamide / 1 h / Heating

2: 85 percent / CH₃CO₂K / 0.5 h / Heating

With sodium ethanolate; potassium acetate; In N,N-dimethyl-formamide;

DOI:10.1007/BF00504208

upstream raw materials:

acetic anhydride

2-amino-4-phenyl-5-acetyl-3-cyano-4H-pyrano<3,2-b>indole

1-acetyl-2,3-dihydro-1H-indol-3-one

1-acetyl-2-benzylideneindolin-3-one

Downstream raw materials:

2-acetylamino-4-phenyl-3-cyano-4H-pyrano<3,2-b>indole