diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

Base Information

Chemical Name:diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide
CAS No.:1301127-23-0
Molecular Formula:C₁₇H₂₀N₂O₈
Molecular Weight:380.354
Hs Code.:

Synonyms:diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

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Technology Process of diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

There total 1 articles about diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1212-20-0
4-Nitro-1-β-nitrobutenyl-benzol

: 685-87-0
Diethyl 2-bromomalonate

: diethyl (R)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

: 1301127-23-0
diethyl (S)-3-ethyl-4-(4-nitrophenyl)-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide

Guidance literature:: With caesium carbonate; (SS)-3,4,5-trifluorophenyl-NAS bromide; In water; 1,3,5-trimethyl-benzene; at -35 ℃; for 12h; optical yield given as %ee; enantioselective reaction;
DOI:10.1039/c0cc05786j