(3-Bromo-4-methoxy-benzyl)-dimethylamine

Base Information

Chemical Name:(3-Bromo-4-methoxy-benzyl)-dimethylamine
CAS No.:774-82-3
Molecular Formula:C₁₀H₁₄BrNO
Molecular Weight:244.131
Hs Code.:
DSSTox Substance ID:DTXSID601239941

Synonyms:(3-bromo-4-methoxy-benzyl)-dimethylamine;774-82-3;SCHEMBL2495130;TQP0136;CXKNKSIXOWIZTJ-UHFFFAOYSA-N;DTXSID601239941;AKOS009027826;3-bromo-4-methoxy-N,N-dimethylbenzylamine;3-Bromo-4-methoxy-N,N-dimethylbenzenemethanamine;1-(3-bromo-4-methoxyphenyl)-N,N-dimethylmethanamine;1-(3-bromo-4-methoxyphenyl)-N,N-dimethyl methane amine

Suppliers and Price of (3-Bromo-4-methoxy-benzyl)-dimethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3-Bromo-4-methoxy-benzyl)-dimethylamine

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:243.02588
Heavy Atom Count:13
Complexity:152

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CC1=CC(=C(C=C1)OC)Br

Technology Process of (3-Bromo-4-methoxy-benzyl)-dimethylamine

There total 3 articles about (3-Bromo-4-methoxy-benzyl)-dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 3-bromo-4-methoxy-N,N-dimethylbenzamide

: 774-82-3
1-(3-bromo-4-methoxyphenyl)-N,N-dimethylmethanamine

Guidance literature:: With sodium hydride; zinc(II) chloride; In tetrahydrofuran; mineral oil; at 60 ℃; for 0.67h; Sealed tube;
DOI:10.1002/anie.201900233

Reference yield:

: 99-58-1
3-bromo-4-methoxybenzoic acid

: 774-82-3
1-(3-bromo-4-methoxyphenyl)-N,N-dimethylmethanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 2 h / 23 °C

1.2: 2 h / 0 - 23 °C

2.1: sodium hydride; zinc(II) chloride / tetrahydrofuran; mineral oil / 0.67 h / 60 °C / Sealed tube

With oxalyl dichloride; sodium hydride; zinc(II) chloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201900233