(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

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Chemical Name:(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate
CAS No.:1364814-43-6
Molecular Formula:C₄₄H₄₅N₃O₁₀
Molecular Weight:775.855
Hs Code.:

Synonyms:(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

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Chemical Property of (6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

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Technology Process of (6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

There total 4 articles about (6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1364814-32-3
C₃₁H₂₈N₂O₅

: 106664-96-4
bis(2,5-dioxopyrrolidin-1-yl) nonanedioate

: 1364814-43-6
(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bmcl.2012.01.024

Reference yield:

: 2861-28-1
1,3-benzodioxole-5-acetic acid

: 1364814-43-6
(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloroform / 1 h / 20 °C

1.2: 20 - 75 °C

2.1: triethylamine / dichloromethane / 0 - 20 °C

With triethylamine; In dichloromethane; chloroform; 1.1: Ugi reaction / 1.2: Ugi reaction;
DOI:10.1016/j.bmcl.2012.01.024

Reference yield:

: 88333-03-3,10340-91-7
Benzyl isocyanide

: 1364814-43-6
(6-(1-(2-(benzo[d][1,3]dioxol-5-yl)-N-cyclopropylacetamido)-2-(benzylamino)-2-oxoethyl)naphthalen-2-yl) (2,5-dioxopyrrolidin-1-yl) nonanedioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloroform / 1 h / 20 °C

1.2: 20 - 75 °C

2.1: triethylamine / dichloromethane / 0 - 20 °C

With triethylamine; In dichloromethane; chloroform; 1.1: Ugi reaction / 1.2: Ugi reaction;
DOI:10.1016/j.bmcl.2012.01.024