(±)-Cbz-βAla-Phe-OH

Base Information

• Chemical Name: (±)-Cbz-βAla-Phe-OH
• CAS No.: 21612-32-8
• Molecular Formula: C₂₀H₂₂N₂O₅
• Molecular Weight: 370.405
• Mol file: 21612-32-8.mol

Synonyms:(±)-Cbz-βAla-Phe-OH

Chemical Property of (±)-Cbz-βAla-Phe-OH

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

CARBOBENZYLOXY-BETA-ALANYL-L-PHENYLALANINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-Cbz-βAla-Phe-OH

There total 5 articles about (±)-Cbz-βAla-Phe-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-benzyloxycarbonyl-3-aminopropionic acid succinimide ester (53733-97-4) + Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → (±)-Cbz-βAla-Phe-OH (21612-32-8)

Guidance literature:

With sodium hydrogencarbonate; In ethanol; water; acetone; at 20 ℃; for 5h;

DOI:10.1002/ejoc.201501366

Reference yield:

3-(benzyloxycarbonylamino)propanoic acid (2304-94-1) + Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → (±)-Cbz-βAla-Phe-OH (21612-32-8)

Guidance literature:

With sodium hydroxide; thionyl chloride; diethyl ether;

DOI:10.1021/ja01288a039

Reference yield:

N-(N-benzyloxycarbonyl-β-alanyl)-phenylalanine ethyl ester → (±)-Cbz-βAla-Phe-OH (21612-32-8)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

3-(benzyloxycarbonylamino)propanoic acid

Phenylalanine

phenylalanine ethyl ester

N-benzyloxycarbonyl-3-aminopropionic acid succinimide ester

Downstream raw materials:

N-β-alanyl-phenylalanine