Chemical Property of 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride
Chemical Property:
- Vapor Pressure:3.37E-09mmHg at 25°C
- Boiling Point:475.2°C at 760 mmHg
- Flash Point:137.4°C
- PSA：21.70000
- LogP:5.78320
- Storage Temp.:Desiccate at RT
- Solubility.:H2O: soluble15mg/mL, clear
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:12
- Exact Mass:391.2278070
- Heavy Atom Count:27
- Complexity:337
- Purity/Quality:
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98%,99%, *data from raw suppliers
NE 100 hydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCCN(CCC)CCC1=CC(=C(C=C1)OC)OCCC2=CC=CC=C2.Cl
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Description
NE-100 (149409-57-4) is potent inhibitor of the sigma receptor (σ) with selectivity for sigma-1 (IC50?= 1.5 nM) over sigma-2 (IC50?= 85 nM).1,2?NE-100 suppressed ischemia-induced neuronal cell death in mice?via?upregulation of GRP78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma-1-independent manner.3
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Uses
NE-100 is a potent and selective σ1 receptor antagonist.
