(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Base Information

Chemical Name:(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile
CAS No.:96845-34-0
Molecular Formula:C₂₁H₂₉NO
Molecular Weight:311.467
Hs Code.:

Synonyms:(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Suppliers and Price of (R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

There total 5 articles about (R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64190-52-9
(8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol

: 96845-34-0
(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Guidance literature:: Multi-step reaction with 5 steps

1: NaH / dimethylformamide

2: dimethylformamide / 18 h / 23 °C

3: n-Bu₄NF / tetrahydrofuran / 4 h / 23 °C

4: C₅H₅N / 3 h / 23 °C

5: dimethylformamide / 20 h / 55 - 60 °C

With pyridine; tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo00214a046

Reference yield:

: 96845-30-6
(1R,3aR,4S,7aR)-1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-7a-methyloctahydro-1H-inden-4-ol

: 96845-34-0
(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylformamide / 18 h / 23 °C

2: n-Bu₄NF / tetrahydrofuran / 4 h / 23 °C

3: C₅H₅N / 3 h / 23 °C

4: dimethylformamide / 20 h / 55 - 60 °C

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo00214a046

Reference yield:

: 96845-31-7
(S)-2-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-propan-1-ol

: 96845-34-0
(R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyronitrile

Guidance literature:: Multi-step reaction with 2 steps

1: C₅H₅N / 3 h / 23 °C

2: dimethylformamide / 20 h / 55 - 60 °C

With pyridine; In N,N-dimethyl-formamide;
DOI:10.1021/jo00214a046