C₄₃H₇₄FNO₇

Base Information

• Chemical Name: C₄₃H₇₄FNO₇
• CAS No.: 1354747-56-0
• Molecular Formula: C₄₃H₇₄FNO₇
• Molecular Weight: 736.061
• Mol file: 1354747-56-0.mol

Synonyms:C₄₃H₇₄FNO₇

Chemical Property of C₄₃H₇₄FNO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₇₄FNO₇

There total 29 articles about C₄₃H₇₄FNO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H24ClFO + C26H51NO6 → C43H74FNO7 (1354747-56-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; methanol; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol2032448

Reference yield:

1-deoxy-1-allyl-2,3,4,6-tetra-O-acetyl-D-galactopyranoside (201279-58-5) → C43H74FNO7 (1354747-56-0)

Guidance literature:

Multi-step reaction with 19 steps

1.1: methanol; sodium methylate / 1 h / 20 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

5.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

6.1: tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; 2-phenyl-1,4-benzoquinone / dichloromethane / 0.08 h / 55 °C / Inert atmosphere; Molecular sieve

6.2: 48 h / 55 °C / Inert atmosphere; Molecular sieve

7.1: sodium methylate / methanol / 2 h / 20 °C / Inert atmosphere

7.2: 20 °C / Inert atmosphere

8.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate / dichloromethane / 0.75 h / -40 °C / Inert atmosphere; Molecular sieve

8.2: 24 h / -40 - -20 °C / Inert atmosphere

9.1: 1H-imidazole; iodine; triphenylphosphine / diethyl ether; benzene / 0.67 h / 20 °C / Inert atmosphere

10.1: zinc / ethanol / 0.75 h / Inert atmosphere; Reflux

11.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / Inert atmosphere; Reflux

12.1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

13.1: water; potassium carbonate / methanol / 20 °C / Inert atmosphere

14.1: triethylamine; trifluoroacetic anhydride / dichloromethane / 0.25 h / 0 °C / Inert atmosphere

15.1: tributyltin methoxide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

16.1: sodium hydroxide / tetrahydrofuran; ethanol; water / 4 h / 20 °C / Inert atmosphere

17.1: water; potassium hydroxide / ethanol / 1 h / Sealed vial; Reflux

18.1: ammonia; sodium / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere

18.2: -78 °C / Inert atmosphere

19.1: triethylamine / tetrahydrofuran; methanol / 2 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; titanium(IV) isopropylate; methanol; tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); L-(+)-diisopropyl tartrate; tetrabutyl ammonium fluoride; ammonia; water; iodine; sodium methylate; tributyltin methoxide; sodium; sodium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2-phenyl-1,4-benzoquinone; trifluoroacetic anhydride; potassium hydroxide; sodium hydroxide; zinc; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil; benzene; 8.1: Sharpless epoxidation / 8.2: Sharpless epoxidation / 18.1: Birch reduction;

DOI:10.1021/ol2032448

Reference yield:

C31H36O5 (1354747-41-3) → C43H74FNO7 (1354747-56-0)

Guidance literature:

Multi-step reaction with 14 steps

1.1: tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; 2-phenyl-1,4-benzoquinone / dichloromethane / 0.08 h / 55 °C / Inert atmosphere; Molecular sieve

1.2: 48 h / 55 °C / Inert atmosphere; Molecular sieve

2.1: sodium methylate / methanol / 2 h / 20 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

3.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate / dichloromethane / 0.75 h / -40 °C / Inert atmosphere; Molecular sieve

3.2: 24 h / -40 - -20 °C / Inert atmosphere

4.1: 1H-imidazole; iodine; triphenylphosphine / diethyl ether; benzene / 0.67 h / 20 °C / Inert atmosphere

5.1: zinc / ethanol / 0.75 h / Inert atmosphere; Reflux

6.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / Inert atmosphere; Reflux

7.1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

8.1: water; potassium carbonate / methanol / 20 °C / Inert atmosphere

9.1: triethylamine; trifluoroacetic anhydride / dichloromethane / 0.25 h / 0 °C / Inert atmosphere

10.1: tributyltin methoxide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

11.1: sodium hydroxide / tetrahydrofuran; ethanol; water / 4 h / 20 °C / Inert atmosphere

12.1: water; potassium hydroxide / ethanol / 1 h / Sealed vial; Reflux

13.1: ammonia; sodium / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere

13.2: -78 °C / Inert atmosphere

14.1: triethylamine / tetrahydrofuran; methanol / 2 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; titanium(IV) isopropylate; tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); L-(+)-diisopropyl tartrate; ammonia; water; iodine; sodium methylate; tributyltin methoxide; sodium; potassium carbonate; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2-phenyl-1,4-benzoquinone; trifluoroacetic anhydride; potassium hydroxide; sodium hydroxide; zinc; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; benzene; 3.1: Sharpless epoxidation / 3.2: Sharpless epoxidation / 13.1: Birch reduction;

DOI:10.1021/ol2032448

upstream raw materials:

1-deoxy-1-allyl-2,3,4,6-tetra-O-acetyl-D-galactopyranoside

C₃₁H₃₆O₅

C₃₃H₃₈O₇

C₃₁H₃₆O₆