(-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol

Base Information

• Chemical Name: (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol
• CAS No.: 289051-61-2
• Molecular Formula: C₁₃H₁₉NO₂S
• Molecular Weight: 253.365
• Mol file: 289051-61-2.mol

Synonyms:(-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol

Chemical Property of (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol

There total 2 articles about (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

(-)-(1R)-1-[(1',1'-dimethylethoxycarbonyl)amino]-2-(methylsulfonyl)oxy-1-phenylethane (102089-75-8) → (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol (289051-61-2) + (4R)-phenyl-2-oxazolidinone (90319-52-1,7480-32-2)

Guidance literature:

(-)-(1R)-1-[(1',1'-dimethylethoxycarbonyl)amino]-2-(methylsulfonyl)oxy-1-phenylethane; With potassium thioacetate; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

With ammonia; In tetrahydrofuran; methanol; at 20 ℃; for 0.166667h; Saturated solution;

DOI:10.1515/znb-2009-0117

Reference yield:

→ (-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol (289051-61-2)

Guidance literature:

Reference yield:

(-)-(2R)-[(1',1'-dimethylethoxycarbonyl)amino]-2-phenylethanethiol (289051-61-2) + diethyl chlorophosphate (814-49-3) → Diethyl-(2R)-S-(2-t-butoxycarbonylamino-2-phenyl)ethanephosphorothioate

Guidance literature:

With 2-(Dimethylamino)pyridine; sodium chloride; In pyridine;

upstream raw materials:

(-)-(1R)-1-[(1',1'-dimethylethoxycarbonyl)amino]-2-(methylsulfonyl)oxy-1-phenylethane