Olmesartan

Base Information

• Chemical Name: Olmesartan
• CAS No.: 144689-24-7
• Molecular Formula: C24H26N6O3
• Molecular Weight: 446.50
• Hs Code.: 29339900
• European Community (EC) Number: 646-413-5
• NSC Number: 759810
• UNII: 8W1IQP3U10
• DSSTox Substance ID: DTXSID2040571
• Nikkaji Number: J715.876I
• Wikipedia: Olmesartan
• Wikidata: Q421156
• NCI Thesaurus Code: C66253
• RXCUI: 321064
• Metabolomics Workbench ID: 42669
• ChEMBL ID: CHEMBL1516
• Mol file: 144689-24-7.mol

Synonyms:4-(hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid;CS-088;olmesartan;omesartan;RNH 6270

Chemical Property of Olmesartan

Chemical Property:

• Appearance/Colour: White solid
• Melting Point: 186-188 °C
• Boiling Point: 738.3 °C at 760 mmHg
• PKA: 2.39±0.50(Predicted)
• Flash Point: 400.3 °C
• PSA: 129.81000
• Density: 1.33 g/cm³
• LogP: 3.65660
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 8
• Exact Mass: 446.20663871
• Heavy Atom Count: 33
• Complexity: 656

Purity/Quality:

99% , ^*data from raw suppliers

Olmesartan ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Drug Classes: Angiotensin II Receptor Antagonists
• Canonical SMILES: CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)C(C)(C)O
• Recent ClinicalTrials: Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)
• Recent EU Clinical Trials: Seeking the ideal anti-hypertensive therapy in obesity-related hypertension. An open-label, single center, randomized clinical trial.
• Recent NIPH Clinical Trials: Prospective, randomized, open-label,clinical trial comparing the effects of olmesartan and imidapril on blood pressure, endothelial function and makers for obesity/oxidative stress/chronic kidney diseases
• Uses: An labelled angiotensin II receptor antagonist. Used as an anti-hypertensive An angiotensin II receptor antagonist. Used as an anti-hypertensive Angiotensin II inhibitor, antihypertensive An angiotensin II (AT1) receptor antagonist Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive.