4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester

Base Information

• Chemical Name: 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester
• CAS No.: 117076-67-2
• Molecular Formula: C₁₂H₁₂Br₂O₄
• Molecular Weight: 380.033
• Mol file: 117076-67-2.mol

Synonyms:4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester

Chemical Property of 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester

There total 3 articles about 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

methyl (E)-4-(3-methoxy-3-oxoprop-1-en-1-yl)benzoate (52148-89-7) → 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester (117076-67-2)

Guidance literature:

With bromine; In chloroform;

DOI:10.1002/hlca.19880710214

Reference yield:

4-Carboxybenzaldehyde (619-66-9) → 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester (117076-67-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / piperidine / pyridine / 12 h / Heating

2: 91 percent / TsOH / 24 h / Heating

3: 81 percent / Br₂ / CHCl₃

With piperidine; bromine; toluene-4-sulfonic acid; In pyridine; chloroform;

DOI:10.1002/hlca.19880710214

Reference yield:

methyl (E)-4-carboxyl cinnamate (115974-97-5) → 4-<1,2-Dibrom-2-(methoxycarbonyl)ethyl>benzoesaeure-methylester (117076-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / TsOH / 24 h / Heating

2: 81 percent / Br₂ / CHCl₃

With bromine; toluene-4-sulfonic acid; In chloroform;

DOI:10.1002/hlca.19880710214

upstream raw materials:

methyl (E)-4-(3-methoxy-3-oxoprop-1-en-1-yl)benzoate

4-Carboxybenzaldehyde

methyl (E)-4-carboxyl cinnamate