2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

Base Information

Chemical Name:2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride
CAS No.:1435488-94-0
Molecular Formula:C₂₅H₂₁N₃O*ClH
Molecular Weight:415.922
Hs Code.:

Synonyms:2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

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Technology Process of 2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

There total 6 articles about 2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1435488-81-5
C₂₅H₂₁N₃O

: 1435488-94-0
2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.25h;
DOI:10.1002/chem.201202593

Reference yield: 40.0%

: 106-38-7
para-bromotoluene

: 1435488-85-9
2-(4-methoxyphenyl)-6-phenyl-1H-imidazo[1,2-b]pyrazole hydrochloride

: 1435488-94-0
2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

Guidance literature:: With hydrogenchloride; palladium acetate; potassium carbonate; tricyclohexylphosphine; In 1,4-dioxane; at 160 ℃; for 4h; Inert atmosphere; Microwave irradiation;
DOI:10.1002/chem.201202593

Reference yield:

: 827-41-8
3-phenylpyrazol-5-amine

: 1435488-94-0
2-(4-methoxyphenyl)-6-phenyl-3-(p-tolyl)-1H-imidazo[1,2-b]pyrazole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / acetonitrile / 24 h / 40 °C

2: hydrogenchloride / water; ethanol / 24 h / 20 °C

3: hydrogenchloride; palladium acetate; potassium carbonate; tricyclohexylphosphine / 1,4-dioxane / 4 h / 160 °C / Inert atmosphere; Microwave irradiation

With hydrogenchloride; palladium acetate; sodium carbonate; potassium carbonate; tricyclohexylphosphine; In 1,4-dioxane; ethanol; water; acetonitrile;
DOI:10.1002/chem.201202593