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Technology Process of Calmidazolium chloride

Calmidazolium chloride

Base Information
  • Chemical Name:Calmidazolium chloride
  • CAS No.:57265-65-3
  • Molecular Formula:C31H23 Cl6 N2 O . Cl
  • Molecular Weight:687.7
  • Hs Code.:29332990
  • European Community (EC) Number:844-044-6
  • UNII:8CQN259H2W
  • DSSTox Substance ID:DTXSID501017259
  • Wikidata:Q27270198
  • ChEMBL ID:CHEMBL1208858
Calmidazolium chloride

Synonyms:1-(bis(chlorophenyl)methyl)-3-(2,4-dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl)imidazolinium chloride;calmidazolium;calmidazolium chloride;calmidazolium ion;R 24571;R-24571

Suppliers and Price of Calmidazolium chloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Calmidazolium chloride
  • 10mg
  • $ 403.00
  • TRC
  • Calmidazolium Chloride
  • 50mg
  • $ 575.00
  • Tocris
  • Calmidazolium Chloride ≥95%(HPLC)
  • 10
  • $ 160.00
  • Sigma-Aldrich
  • Calmidazolium chloride solid
  • 10mg
  • $ 135.00
  • Sigma-Aldrich
  • Calmidazolium Chloride A cell-permeable calmodulin antagonist.
  • 10mg
  • $ 129.50
  • Sigma-Aldrich
  • Calmidazolium chloride solid
  • 5mg
  • $ 190.00
  • Sigma-Aldrich
  • Calmidazolium chloride solid
  • 25mg
  • $ 714.00
  • Sigma-Aldrich
  • Calmidazolium chloride solid
  • 50mg
  • $ 1010.00
  • DC Chemicals
  • Calmidazoliumchloride(R24571) >98%
  • 250 mg
  • $ 1100.00
  • DC Chemicals
  • Calmidazoliumchloride(R24571) >98%
  • 100 mg
  • $ 550.00
Total 15 raw suppliers
Chemical Property of Calmidazolium chloride
Chemical Property:
  • Melting Point:172-176 °C  
  • Boiling Point:724.9°Cat760mmHg 
  • Flash Point:392.2°C 
  • PSA：18.04000 
  • Density:g/cm3 
  • LogP:7.29580 
  • Storage Temp.:2-8°C 
  • Water Solubility.:Soluble in dimethyl sulfoxide, ethanol. methanol, chloroform, and propylene glycol. Insoluble in water. 
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:9
  • Exact Mass:685.960057
  • Heavy Atom Count:41
  • Complexity:742
Purity/Quality:

98%,99%, *data from raw suppliers

Calmidazolium chloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 22-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)N3C=C[N+](=C3)CC(C4=C(C=C(C=C4)Cl)Cl)OCC5=C(C=C(C=C5)Cl)Cl)Cl.[Cl-]
  • Uses Calmidazolium chloride is a small molecule CaM antagonist and calcium channel protein inhibitor. Calmidazolium chloride demonstrates noncompetitive inhibition of platelet and sarcoplasmic reticulum Ca2+-ATPase activity and shows inhibition of Ca2+?transport activity in platelet microsomes. In HeLa cells, calmidazolium chloride stimulates a mechanism of cellular Ca2+?influx distinct from store-operated Ca2+?entry and unaccompanied by Ca2+?store depletion, mobilizing stores and evoking a Ca2+?signal through activation of phospholipase C. Calmidazolium chloride is described to inhibit constitutive nitric oxide synthase (NOS) activity without affecting inducible NOS in rat aorta. The dependence upon calmodulin of neuronal NOS (nNOS) in neuroblastoma N1E-115 cells was probed with calmidazolium chloride, where it was demonstrated to increase cGMP levels indirectly indicating an increase in NO output by nNOS. Calmidazolium chloride is also described to inhibit the activity of calmodulin N-methyltransferase.
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