ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

Base Information

Chemical Name:ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate
CAS No.:127791-91-7
Molecular Formula:C₃₄H₃₁NO₃
Molecular Weight:501.625
Hs Code.:

Synonyms:ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

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Chemical Property of ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

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Technology Process of ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

There total 1 articles about ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 39208-08-7
ethyl 3-<2-(benzyloxy)phenyl>-3-oxopropanoate

: 33554-91-5
2-((3,5-dimethylphenyl)amino)-1-phenylethane-1-one

: 127791-91-7
ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

Guidance literature:: With 3,5-dimethylaniline hydrobromide; zinc(II) chloride; In benzene; Heating;
DOI:10.1021/jm00171a047

Reference yield: 54.0%

: 127791-91-7
ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

: 127791-99-5
1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 48h; Heating;
DOI:10.1021/jm00171a047

Reference yield:

: 127791-91-7
ethyl 1-(3,5-dimethylphenyl)-2-<2-(benzyloxy)phenyl>-4-phenylpyrrole-3-carboxylate

: 127791-82-6
1,4-dihydro-1-(3,5-dimethylphenyl)-3-phenyl<1>benzopyrano<4,3-b>pyrrol-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / sodium hydroxide / ethanol / 48 h / Heating

2: 54 percent / H₂ / 10percent Pd/C / ethyl acetate / 2068.6 Torr

3: 50 percent / thionyl chloride / diethyl ether / Heating

With sodium hydroxide; thionyl chloride; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol; ethyl acetate;
DOI:10.1021/jm00171a047