3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene

Base Information

• Chemical Name: 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene
• CAS No.: 1394035-44-9
• Molecular Formula: C₃₃H₃₂O₆
• Molecular Weight: 524.613
• Mol file: 1394035-44-9.mol

Synonyms:3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene

Chemical Property of 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene

There total 15 articles about 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

3,3-diphenyl-2-propenal (1210-39-5) + 2,3,5,6,8,9,11,12-octahydronaphtho[2,3-b][1,4,7,10,13]pentaoxacyclopentadecin-16-ol (1394035-43-8) → 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene (1394035-44-9)

Guidance literature:

With titanium(IV) tetraethanolate; In toluene; at 100 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2012.07.029

Reference yield: 16.0%

2,3,5,6,8,9,11,12-octahydronaphtho[2,3-b][1,4,7,10,13]pentaoxacyclopentadecin-16-ol (1394035-43-8) + 1,1-diphenyl-2-propyn-1-ol (3923-52-2) → 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene (1394035-44-9)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 70 - 80 ℃;

DOI:10.1016/j.tet.2012.07.029

Reference yield: 14.0%

8,9-bis(2-hydroxyethoxy)-3,3-diphenyl-3H-benzo[f]chromene + diethylene glycol ditosylate (7460-82-4) → 3,3-diphenyl-9,10,12,13,15,16,18,19-octahydro-3H-[1,4,7,10,13]pentaoxacyclopentadeca[2′,3′:4,5]benzo[f]chromene (1394035-44-9)

Guidance literature:

8,9-bis(2-hydroxyethoxy)-3,3-diphenyl-3H-benzo[f]chromene; With tetra-(n-butyl)ammonium iodide; sodium hydroxide; In water; toluene; for 0.5h;

diethylene glycol ditosylate; In water; toluene; for 16h; Reflux;

DOI:10.1055/s-0033-1341063

upstream raw materials:

3,3-diphenyl-2-propenal

2,3,5,6,8,9,11,12-octahydronaphtho[2,3-b][1,4,7,10,13]pentaoxacyclopentadecin-16-ol

1,1-diphenyl-2-propyn-1-ol

2,3,5,6,8,9,11,12-octahydronaphtho[2,3-b][1,4,7,10,13]pentaoxacyclopentadecin-16-yl acetate