2-(Pentafluoroethyl)-2-phenylpiperidine

Base Information

Chemical Name:2-(Pentafluoroethyl)-2-phenylpiperidine
CAS No.:887361-05-9
Molecular Formula:C₁₃H₁₄F₅N
Molecular Weight:279.253
Hs Code.:
DSSTox Substance ID:DTXSID901023248
Mol file:887361-05-9.mol

Synonyms:2-(Pentafluoroethyl)-2-phenylpiperidine;887361-05-9;WWLRITZRPVWXPB-UHFFFAOYSA-N;DTXSID901023248;AKOS005143877;2-(1,1,2,2,2-pentafluoroethyl)-2-phenylpiperidine

Suppliers and Price of 2-(Pentafluoroethyl)-2-phenylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(Pentafluoroethyl)-2-phenylpiperidine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:279.10464026
Heavy Atom Count:19
Complexity:309

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCNC(C1)(C2=CC=CC=C2)C(C(F)(F)F)(F)F

Technology Process of 2-(Pentafluoroethyl)-2-phenylpiperidine

There total 1 articles about 2-(Pentafluoroethyl)-2-phenylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 57050-07-4
2-phenyl-3,4,5,6-tetrahydropyridine

: 354-33-6
1,1,1,2,2-pentafluoroethane

: 887361-05-9
2-phenyl-2-(pentafluoroethyl)piperidine

Guidance literature:: 1,1,1,2,2-pentafluoroethane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

2-phenyl-3,4,5,6-tetrahydropyridine; With boron trifluoride diethyl etherate; In tetrahydrofuran; hexane; at -78 ℃; for 6h; Further stages.;
DOI:10.1016/j.jfluchem.2008.01.013