2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride

Base Information

• Chemical Name: 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride
• CAS No.: 1176126-32-1
• Molecular Formula: C₉H₇ClF₄O₃S
• Molecular Weight: 306.665
• Mol file: 1176126-32-1.mol

Synonyms:2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride

Chemical Property of 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride

There total 1 articles about 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(2-fluoroethoxy)-6-trifluoromethylphenyl propyl sulfde (1176126-27-4) → 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride (1176126-32-1)

Guidance literature:

With chlorine; acetic acid; In water; at 45 - 55 ℃;

DOI:10.1016/j.bmc.2009.02.010

Reference yield: 52.0%

2-amino-5,8-dimethoxy[1,2,4]triazolo-[1,5-c]pyrimidine (219715-62-5) + 2-(2-fluoroethoxy)-6-trifluoromethylbenzenesulfonyl chloride (1176126-32-1) → 2-(2-fluoroethoxy)-6-trifluoromethyl-N-(5,8-dimethoxy-1,2,4-triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide (219714-72-4)

Guidance literature:

With pyridine; dimethyl sulfoxide; In acetonitrile; for 6h;

DOI:10.1016/j.bmc.2009.02.010

upstream raw materials:

2-(2-fluoroethoxy)-6-trifluoromethylphenyl propyl sulfde

Downstream raw materials:

2-(2-fluoroethoxy)-6-trifluoromethyl-N-(5,8-dimethoxy-1,2,4-triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide