Etryptamine

Base Information

• Chemical Name: Etryptamine
• CAS No.: 2235-90-7
• Deprecated CAS: 6152-12-1
• Molecular Formula: C12H16 N2
• Molecular Weight: 188.27
• NSC Number: 88061
• UNII: GR181O3R32
• DSSTox Substance ID: DTXSID1046764
• Nikkaji Number: J7.373C
• Wikipedia: Alpha-Ethyltryptamine
• Wikidata: Q2394183
• NCI Thesaurus Code: C72772
• ChEMBL ID: CHEMBL1619758
• Mol file: 2235-90-7.mol

Synonyms:2-ethyltryptamine;3-(2-aminobutylindole);alpha-ethyltryptamine;etryptamine;etryptamine acetate, (+-)-isomer of etryptamine;etryptamine hydrochloride;etryptamine monoacetate;etryptamine monoacetate, (+)-isomer;etryptamine monoacetate, (+-)-isomer;etryptamine monoacetate, (-)-isomer;etryptamine, (+)-isomer

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Etryptamine

Chemical Property:

• Melting Point: 97-99°
• Refractive Index: 1.5600 (estimate)
• Boiling Point: 356.2°Cat760mmHg
• PKA: 17.22±0.30(Predicted)
• Flash Point: 196.5°C
• PSA: 41.81000
• Density: 1.096g/cm³
• LogP: 3.14800
• Water Solubility.: 0.51g/L(room temperature)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 188.131348519
• Heavy Atom Count: 14
• Complexity: 181

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(CC1=CNC2=CC=CC=C21)N
• Uses: α-Ethyltryptamine (E931900) is used as a stimulant and entactogen that have actions at multiple central nervous system (CNS) receptor sites.
• Therapeutic Function: Central stimulant

Technology Process of Etryptamine

There total 7 articles about Etryptamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-(2-nitro-butyl)-indole (835-41-6) → etryptamine (2235-90-7)

Guidance literature:

With samarium diiodide; water; isopropylamine; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2007.05.105

Reference yield:

3-(2-nitrobut-1-en-1-yl)-1H-indole (65283-34-3) → etryptamine (2235-90-7)

Guidance literature:

With chloro-trimethyl-silane; borane; In tetrahydrofuran; at 20 ℃; for 14h;

DOI:10.1016/j.bmcl.2006.10.058

Reference yield:

→ etryptamine (2235-90-7)

Guidance literature:

With ethanol; nickel; Hydrieren an Platin;

DOI:10.1021/ja01204a061

upstream raw materials:

3-(2-nitro-but-1-enyl)-indole

3-(2-nitrobut-1-en-1-yl)-1H-indole

3-(2-nitro-butyl)-indole

Indole-3-carboxaldehyde

Downstream raw materials:

{(3R,6S,15S)-3-Benzyl-15-[1-(1H-indol-3-ylmethyl)-propylcarbamoyl]-2,5,9-trioxo-1,4,10-triaza-cyclopentadec-6-yl}-carbamic acid tert-butyl ester

Refernces

• 1、 -. "BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION". Paragraph 0200. . Retrieved 2017/02/24.
• 2、 Marshall, Daniel R.,Rodriguez, Gus,Thomson, David S.,Nelson, Richard,Capolina, Allison. "α-Methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands". . p. 315 - 319. Retrieved 2007/10/03.