P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester

Base Information

• Chemical Name: P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester
• CAS No.: 486429-69-0
• Molecular Formula: C₁₄H₂₅PSSeSi
• Molecular Weight: 363.438
• Mol file: 486429-69-0.mol

Synonyms:P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester

Chemical Property of P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester

There total 4 articles about P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S₀[2-(trimethylsilyl)ethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

Dichlorophenylphosphine (644-97-3) + lithium 2-(trimethylsilyl)ethanethiolate → P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S0[2-(trimethylsilyl)ethyl] ester (486429-69-0)

Guidance literature:

Dichlorophenylphosphine; isopropylmagnesium halide; In tetrahydrofuran; at -78 ℃; for 1h;

lithium 2-(trimethylsilyl)ethanethiolate; at -78 ℃; for 0.25h;

With selenium; at 20 ℃; for 2h;

DOI:10.1246/cl.2002.914

Reference yield:

ethenyltrimethylsilane (754-05-2) → P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S0[2-(trimethylsilyl)ethyl] ester (486429-69-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / 23 / 1 h / Heating

2: 78 percent / EtONa / tetrahydrofuran / 12 h / 20 °C

3: tetrahydrofuran / 0 °C

With sodium ethanolate; 23; In tetrahydrofuran;

DOI:10.1021/jo050576c

Reference yield:

phosphorodithioic acid O,O-diethyl ester S-[(2-trimethylsilyl)ethyl] ester (861150-48-3) → P-(1-methylethyl)-P-phenylphosphinoselenothioic acid S0[2-(trimethylsilyl)ethyl] ester (486429-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / EtONa / tetrahydrofuran / 12 h / 20 °C

2: tetrahydrofuran / 0 °C

With sodium ethanolate; In tetrahydrofuran;

DOI:10.1021/jo050576c

upstream raw materials:

Dichlorophenylphosphine

2-trimethylsilylethanethiol

P-(1-methylethyl)-P-phenylphosphinoselenoic chloride

phosphorodithioic acid O,O-diethyl ester S-[(2-trimethylsilyl)ethyl] ester