(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

Base Information

Chemical Name:(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one
CAS No.:1229443-08-6
Molecular Formula:C₂₉H₂₃NO₃
Molecular Weight:433.507
Hs Code.:

Synonyms:(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

Suppliers and Price of (R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

Chemical Property:

Purity/Quality:: 95%-98% ^*data from raw suppliers

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Technology Process of (R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

There total 1 articles about (R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1229443-09-7
1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethylidene)-3,4-dihydroquinolin-2(1H)-one

: (S)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

: 1229443-08-6
(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

Guidance literature:: With bis(trimethylsilyl)amide yttrium(III); 4-methoxypyridine N-oxide; 2-(((1S,2R,3R)-3-(diphenylphosphoryl)-2-hydroxycyclohexyl)(methyl)amino)phenol; tetrabutyl-ammonium chloride; In tetrahydrofuran; at -50 ℃; for 36h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja103183r

Reference yield: 93.0%

: 1229443-08-6
(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one

: 72824-04-5
2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 3-((1R,2R)-2-hydroxy-2-(naphthalen-1-yl)-1-phenylpent-4-enyl)-1-(methoxymethyl)quinolin-2(1H)-one

: 1229443-07-5
3-((1R,2S)-2-hydroxy-2-(naphthalen-1-yl)-1-phenylpent-4-enyl)-1-(methoxymethyl)quinolin-2(1H)-one

Guidance literature:: 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With tetra-n-butylphosphonium tetrafluoroborate; CuF*3PPh₃*2EtOH; potassium tert-butylate; zinc(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

(R)-1-(methoxymethyl)-3-(2-(naphthalen-1-yl)-2-oxo-1-phenylethyl)quinolin-2(1H)-one; In tetrahydrofuran; at 20 ℃; for 1h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1021/ja103183r