N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

Base Information

Chemical Name:N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine
CAS No.:353232-77-6
Molecular Formula:C₂₁H₁₉F₃N₂O₃S
Molecular Weight:436.455
Hs Code.:

Synonyms:N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

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Chemical Property of N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

Chemical Property:

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Technology Process of N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

There total 5 articles about N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(4-(3-benzyloxyphenyl))pyridin-3-ylmethylamine

: 1648-99-3
2,2,2-Trifluoroethanesulfonyl chloride

: 353232-77-6
N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

Guidance literature:: With pyridine; In 1,2-dichloro-ethane; at 0 - 20 ℃;

Reference yield:

: 500-22-1
3-pyridinecarboxaldehyde

: 353232-77-6
N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄

2: pyridine

3: NaH

With pyridine; sodium tetrahydroborate; sodium hydride;
DOI:10.1016/j.bmcl.2004.04.017

Reference yield:

: 591-27-5
m-Hydroxyaniline

: 353232-77-6
N-(4-(3-benzyloxyphenyl)-N-(2,2,2-trifluoroethanesulfonyl)pyrid-3-yl)methylamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄

2: pyridine

3: NaH

With pyridine; sodium tetrahydroborate; sodium hydride;
DOI:10.1016/j.bmcl.2004.04.017