N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine

Base Information

• Chemical Name: N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine
• CAS No.: 1290618-20-0
• Molecular Formula: C₁₅H₂₀N₂O₆
• Molecular Weight: 324.334
• Mol file: 1290618-20-0.mol

Synonyms:N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine

Chemical Property of N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine

There total 1 articles about N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

di-tert-butyl dicarbonate (24424-99-5) + 3-methyl-2-nitro-L-phenylalanine hydrochloride (1290618-19-7) → N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine (1290618-20-0)

Guidance literature:

With triethylamine; In water; at 20 ℃;

DOI:10.1021/jo200530j

Reference yield:

2,2,2-trifluoroethyl trifluoromethanesulphonate (6226-25-1) + N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalanine (1290618-20-0) → 2,2,2-trifluoroethyl N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalaninate (1290617-85-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 60 ℃;

DOI:10.1021/ml200204m

upstream raw materials:

di-tert-butyl dicarbonate

3-methyl-2-nitro-L-phenylalanine hydrochloride

Downstream raw materials:

2,2,2-trifluoroethyl N-((tert-butoxy)carbonyl)-3-methyl-2-nitro-L-phenylalaninate