8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Base Information

Chemical Name:8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS No.:5500-76-5
Molecular Formula:C₁₅H₁₉FN₂O₂
Molecular Weight:278.326
Hs Code.:2934999090
Mol file:5500-76-5.mol

Synonyms:8-[2-(4-fluorophenyl)ethyl]-4-oxa-2,8-diazaspiro[4.5]decan-3-one;Oxa-1 oxo-2 diaza-3,8 (p-fluorophenethyl)-8 spiro(4,5)decane;1-Oxa-3,8-diazaspiro(4.5)decan-2-one,8-(p-fluorophenethyl);Oxa-1 oxo-2 diaza-3,8 (p-fluorophenethyl)-8 spiro(4,5)decane [French];

Suppliers and Price of 8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Chemical Property:

Vapor Pressure:2.5E-09mmHg at 25°C
Boiling Point:478.8°Cat760mmHg
Flash Point:243.4°C
PSA：45.06000
Density:1.24g/cm³
LogP:1.52050

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one

There total 4 articles about 8-[2-(4-Fluorophenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23804-68-4
4-(aminomethyl)-1-benzyl-4-hydroxypiperidine

: 5500-76-5
8-(4-fluoro-phenethyl)-1-oxa-3,8-diaza-spiro[4.5]decan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaOEt / ethanol / Heating

2: H₂ / Pd-C / acetic acid

3: KI / butan-2-one / Heating

With hydrogen; sodium ethanolate; potassium iodide; palladium on activated charcoal; In ethanol; acetic acid; butanone;

Reference yield:

: 5053-14-5
8-Benzyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one

: 5500-76-5
8-(4-fluoro-phenethyl)-1-oxa-3,8-diaza-spiro[4.5]decan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C / acetic acid

2: KI / butan-2-one / Heating

With hydrogen; potassium iodide; palladium on activated charcoal; In acetic acid; butanone;