C₅₇H₁₀₀O₉Si₄

Base Information

• Chemical Name: C₅₇H₁₀₀O₉Si₄
• CAS No.: 213824-35-2
• Molecular Formula: C₅₇H₁₀₀O₉Si₄
• Molecular Weight: 1041.76
• Mol file: 213824-35-2.mol

Synonyms:C₅₇H₁₀₀O₉Si₄

Chemical Property of C₅₇H₁₀₀O₉Si₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₇H₁₀₀O₉Si₄

There total 19 articles about C₅₇H₁₀₀O₉Si₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C57H102O9Si4 → C57H100O9Si4 (213824-35-2)

Guidance literature:

With pyridine; sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1002/anie.199725201

Reference yield:

(Z)-2-[(2S,3S,4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-yloxymethyl]-3-[(1S,2R,6R)-6-isopropyl-3-methyl-2-((2S,3S)-3-methyl-2,3-bis-triethylsilanyloxy-pent-4-ynyl)-cyclohex-3-enyl]-propenal (201142-54-3) → C57H100O9Si4 (213824-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: LiHMDS / tetrahydrofuran / 0.17 h / -30 °C

2: NaHCO₃, pyridine, Dess-Martin reagent / CH₂Cl₂ / 0.25 h / 0 °C

With pyridine; sodium hydrogencarbonate; Dess-Martin periodane; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja9810639

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) → C57H100O9Si4 (213824-35-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 97 percent / Et₃N / CH₂Cl₂ / 2 h / 0 °C

2: 80 percent / NBS, pyridine / acetone; H₂O

3: 93 percent / NaH / CH₂Cl₂ / 3.5 h / 25 °C

4: TMSOTf / hexane / -78 °C

5: LiHMDS / tetrahydrofuran / 0.17 h / -30 °C

6: NaHCO₃, pyridine, Dess-Martin reagent / CH₂Cl₂ / 0.25 h / 0 °C

With pyridine; N-Bromosuccinimide; trimethylsilyl trifluoromethanesulfonate; sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; hexane; dichloromethane; water; acetone;

DOI:10.1021/ja9810639

upstream raw materials:

(Z)-2-[(2S,3S,4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-yloxymethyl]-3-[(1S,2R,6R)-6-isopropyl-3-methyl-2-((2S,3S)-3-methyl-2,3-bis-triethylsilanyloxy-pent-4-ynyl)-cyclohex-3-enyl]-propenal

t-butyldimethylsiyl triflate

p-methoxybenzyl chloride

(3aR,6R,7S,7aS)-2,2-Dimethyl-6-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol