N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide

Base Information

• Chemical Name: N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide
• CAS No.: 1213778-80-3
• Molecular Formula: C₂₃H₁₇FN₂O
• Molecular Weight: 356.399
• Mol file: 1213778-80-3.mol

Synonyms:N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide

Chemical Property of N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide

There total 1 articles about N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5-fluoro-2-(2-phenylethynyl)benzaldehyde oxime (1095128-60-1) + 4-methylphenyl isocyanide (7175-47-5) → N-(7-fluoro-3-phenylisoquinolin-1-yl)-N-p-tolylformamide (1213778-80-3)

Guidance literature:

5-fluoro-2-(2-phenylethynyl)benzaldehyde oxime; With silver trifluoromethanesulfonate; In 1,4-dioxane; at 70 ℃; for 1h; Inert atmosphere;

4-methylphenyl isocyanide; With bismuth(lll) trifluoromethanesulfonate; In 1,4-dioxane; at 20 - 30 ℃; Inert atmosphere;

DOI:10.1002/adsc.200900442

upstream raw materials:

5-fluoro-2-(2-phenylethynyl)benzaldehyde oxime

4-methylphenyl isocyanide