1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

Base Information

Chemical Name:1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate
CAS No.:1246248-08-7
Molecular Formula:C₄₆H₆₄N₆O₆
Molecular Weight:797.051
Hs Code.:

1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

Synonyms:1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

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Chemical Property of 1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

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Technology Process of 1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

There total 1 articles about 1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 1246248-07-6
tert-Butyl 4-(4-{3-[(2-{4-[(biphenyl-2-ylcarbamoyl)oxy]piperidin-1-yl}ethyl)(methyl)amino]-3-oxopropyl}piperidin-1-yl)benzoate

: 123183-72-2
N-(tert-butyl)oxycarbonyl-N,N’-trimethyl-1,3-diaminopropane

: 1246248-08-7
1-(2-{[3-(1-{4-[{3-[(tert-butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]phenyl}piperidin-4-yl)propanoyl](methyl)amino}ethyl)piperidin-4-yl biphenyl-2-ylcarbamate

Guidance literature:: tert-Butyl 4-(4-{3-[(2-{4-[(biphenyl-2-ylcarbamoyl)oxy]piperidin-1-yl}ethyl)(methyl)amino]-3-oxopropyl}piperidin-1-yl)benzoate; With hydrogenchloride; In 1,4-dioxane; for 16h; Inert atmosphere;

With pivaloyl chloride; triethylamine; In dichloromethane; for 0.25h; Cooling with ice;

N-(tert-butyl)oxycarbonyl-N,N’-trimethyl-1,3-diaminopropane; In dichloromethane; at 20 ℃; for 16h; Cooling with ice; Inert atmosphere;