Teclozan

Base Information

• Chemical Name: Teclozan
• CAS No.: 5560-78-1
• Molecular Formula: C20H28 Cl4 N2 O4
• Molecular Weight: 502.265
• European Community (EC) Number: 226-934-0
• NSC Number: 107433
• UNII: K9RIF0COUB
• DSSTox Substance ID: DTXSID00204147
• Nikkaji Number: J7.995B
• Wikipedia: Teclozan
• Wikidata: Q7692717
• NCI Thesaurus Code: C152533
• Metabolomics Workbench ID: 154035
• ChEMBL ID: CHEMBL1788387
• Mol file: 5560-78-1.mol

Synonyms:Falmonox;N,N'-(p-phenylenedimethylene)-bis(2,2-dichloro-N- (2-ethoxyethyl))acetamide;teclosan;teclosine;teclozan;teclozine;Win 13 146

Chemical Property of Teclozan

Chemical Property:

• Vapor Pressure: 1.05E-13mmHg at 25°C
• Melting Point: 137.6-143.9°
• Boiling Point: 585.8°Cat760mmHg
• Flash Point: 308.1°C
• PSA: 59.08000
• Density: 1.294g/cm³
• LogP: 4.02420
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 14
• Exact Mass: 502.077368
• Heavy Atom Count: 30
• Complexity: 459

Purity/Quality:

99% ^*data from raw suppliers

TECLOZAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCCN(CC1=CC=C(C=C1)CN(CCOCC)C(=O)C(Cl)Cl)C(=O)C(Cl)Cl

Technology Process of Teclozan

There total 2 articles about Teclozan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dichloroacethyl chloride (79-36-7) + (2-Ethoxy-ethyl)-{4-[(2-ethoxy-ethylamino)-methyl]-benzyl}-amine; hydrochloride → teclozan (5560-78-1)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jm50016a001

Reference yield:

→ teclozan (5560-78-1)

Guidance literature:

1,4-Bis-(2-ethoxy-ethylaminomethyl)-benzol, wss. NaOH, Ethylenchlorid, Dichloracetylchlorid;

upstream raw materials:

dichloroacethyl chloride