Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]

Base Information

Chemical Name:Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]
CAS No.:174740-64-8
Molecular Formula:C₄₅H₆₈N₂O₅
Molecular Weight:717.045
Hs Code.:
Mol file:174740-64-8.mol

Synonyms:Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]

Suppliers and Price of Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]

Chemical Property:

Vapor Pressure:7.36E-30mmHg at 25°C
Boiling Point:838.7°Cat760mmHg
Flash Point:461.1°C
PSA：122.71000
Density:1.098g/cm³
LogP:10.61490

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl]

There total 4 articles about Benzoic acid, 2-[[[7-[[(3.beta.)-3-hydroxy-28-oxolup-20(29)-en-28-yl]a mino]heptyl]amino]carbonyl] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 174740-37-5
Acetic acid (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-[7-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-heptylcarbamoyl]-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysen-9-yl ester

: 174740-64-8
N-{7-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-heptyl}-phthalamic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; for 12h; Ambient temperature;
DOI:10.1021/jm950669u

Reference yield:

: 646-19-5
heptane-1,7-diamine

: 174740-64-8
N-{7-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-heptyl}-phthalamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / CH₂Cl₂ / 15 h / Ambient temperature

2: 90 percent / 1-hydroxybenzotriazole, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, triethylamine / CH₂Cl₂ / 2 h / Ambient temperature

3: 72 percent / 5 N aq. NaOH / methanol; tetrahydrofuran / 12 h / Ambient temperature

With sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm950669u

Reference yield:

: 161795-96-6
A₄₃-D

: 174740-64-8
N-{7-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-heptyl}-phthalamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 1-hydroxybenzotriazole, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride, triethylamine / CH₂Cl₂ / 2 h / Ambient temperature

2: 72 percent / 5 N aq. NaOH / methanol; tetrahydrofuran / 12 h / Ambient temperature

With sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm950669u