1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone

Base Information

• Chemical Name: 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone
• CAS No.: 851189-86-1
• Molecular Formula: C₁₈H₃₄O₂Si
• Molecular Weight: 310.552
• Mol file: 851189-86-1.mol

Synonyms:1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone

Chemical Property of 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone

There total 2 articles about 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-methyl-pent-3-en-2-one (141-79-7) + 2-<(tert-butyldimethylsilyl)oxy>-4,4-dimethyl-1,3-butadiene (130043-07-1) → 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone (851189-86-1)

Guidance literature:

With aluminum tri-bromide; trimethylaluminum; 1,1-dibromomethane; In dichloromethane; toluene; at -5 ℃; for 48h;

DOI:10.1021/ol050361p

Reference yield: 86.0%

3-methyl-1-oxocyclohex-2-en-4-acetic acid methyl ester (67170-56-3) + 2-<(tert-butyldimethylsilyl)oxy>-4,4-dimethyl-1,3-butadiene (130043-07-1) → 1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone (851189-86-1) + methyl 7-[(1,1-dimethylethyl)dimethylsilyloxy]-5,5,8a-trimethyl-4-oxo-1,2,3,4,4a,5,8,8a-octahydronaphthalenylacetate

Guidance literature:

With bis(trifluoromethanesulfonyl)amide; In dichloromethane; at -5 ℃; for 2h;

DOI:10.1021/ol062980j

Reference yield: 100.0%

1-(4-[(1,1-dimethylethyl)dimethylsilyloxy]-2,2,5,5-tetramethylcyclohex-3-enyl)ethanone (851189-86-1) → 3,3,5,5-Tetramethyl-4-acetyl-1-cyclohexanon (16556-46-0)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 23 ℃; for 18h;

DOI:10.1021/ol050361p

upstream raw materials:

4-methyl-pent-3-en-2-one

2-<(tert-butyldimethylsilyl)oxy>-4,4-dimethyl-1,3-butadiene

3-methyl-1-oxocyclohex-2-en-4-acetic acid methyl ester

Downstream raw materials:

3,3,5,5-Tetramethyl-4-acetyl-1-cyclohexanon