N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

Base Information

Chemical Name:N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide
CAS No.:1207201-31-7
Molecular Formula:C₁₈H₁₉FIN₃O₃
Molecular Weight:471.27
Hs Code.:

Synonyms:N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

Suppliers and Price of N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

Chemical Property:

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Technology Process of N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

There total 1 articles about N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1207201-30-6
N-[(3aS,4R,7aR)-2,2-dimethylhexahydro-1,3-benzodioxol-4-yl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

: 1207201-31-7
N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

Guidance literature:: N-[(3aS,4R,7aR)-2,2-dimethylhexahydro-1,3-benzodioxol-4-yl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide; With hydrogenchloride; methanol; In diethyl ether; at 20 ℃; for 5h;

With ammonium hydroxide; In methanol; pH=10;

Reference yield:

: 1207201-31-7
N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide

: 1207201-42-0
N-((1R,2S,3R)-2,3-dihydroxycyclohexyl)-3-(2-fluorophenylamino)isonicotinamide

Guidance literature:: With sodium tetrahydroborate; water; sodium hydroxide; palladium dichloride; In tetrahydrofuran; at 20 ℃; for 48h; Sealed tube;