Technology Process of C19H13F2N3O3
There total 6 articles about C19H13F2N3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
1,4-dioxane; water;
at 50 ℃;
for 0.5h;
DOI:10.1055/s-0031-1290079
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 21 h / 20 °C
3: sodium hydroxide / 1,4-dioxane; water / 0.5 h / 50 °C
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide;
In
1,4-dioxane; dichloromethane; water;
1: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium phosphate / dimethyl sulfoxide / 0.5 h / 100 °C
2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 21 h / 20 °C
4: sodium hydroxide / 1,4-dioxane; water / 0.5 h / 50 °C
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide;
In
1,4-dioxane; dichloromethane; water; dimethyl sulfoxide;
2: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079
