5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester

Base Information

• Chemical Name: 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester
• CAS No.: 866718-67-4
• Molecular Formula: C₆₈H₆₈N₂O₁₁
• Molecular Weight: 1089.29
• Mol file: 866718-67-4.mol

Synonyms:5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester

Chemical Property of 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester

There total 6 articles about 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-(tert-butyl-dimethyl-silanyloxy)-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester (389866-47-1) → 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester (866718-67-4)

Guidance literature:

With zinc tetrafluoroborate; water; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1039/b103798f

Reference yield:

1-bromo-10-decanol (53463-68-6) → 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester (866718-67-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 66 percent / 4 M aq. NaOH / ethanol / 22 h / Heating

2: 81 percent / DMAP; DCC / CH₂Cl₂ / 20 h / 20 °C

3: 95 percent / 4-(dimethylamino)pyridinium toluene-p-sulfonate; DCC; 4-pyrrolidinopyridine / CH₂Cl₂ / 18 h / 20 °C

4: 91 percent / Zn(BF₄)2; H₂O / tetrahydrofuran / 18 h / 20 °C

With dmap; sodium hydroxide; zinc tetrafluoroborate; water; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; 4-(dimethylamino)pyridinium tosylate; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1039/b103798f

Reference yield:

4-Cyano-4'-hydroxybiphenyl (19812-93-2) → 5-hydroxy-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester (866718-67-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 81 percent / DMAP; DCC / CH₂Cl₂ / 20 h / 20 °C

2: 95 percent / 4-(dimethylamino)pyridinium toluene-p-sulfonate; DCC; 4-pyrrolidinopyridine / CH₂Cl₂ / 18 h / 20 °C

3: 91 percent / Zn(BF₄)2; H₂O / tetrahydrofuran / 18 h / 20 °C

With dmap; zinc tetrafluoroborate; water; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; 4-(dimethylamino)pyridinium tosylate; In tetrahydrofuran; dichloromethane;

DOI:10.1039/b103798f

upstream raw materials:

5-(tert-butyl-dimethyl-silanyloxy)-isophthalic acid bis-{10-[4-(4'-cyano-biphenyl-4-yloxycarbonyl)-phenoxy]-decyl} ester

1-bromo-10-decanol

4-Cyano-4'-hydroxybiphenyl

4-[(10-hydroxydecyl)oxy]benzoic acid

Downstream raw materials:

C₈₈H₈₂N₂O₁₂

bis[10-(4-{[(4'-cyanobiphenyl-4-yl)oxy]carbonyl}phenoxy)decyl] 5-{[5-(1,2-dithiolan-3-yl)-pentanoyl]oxy}benzene-1,3-dicarboxylate

bis[10-(4-{[(4'-cyanobiphenyl-4-yl)oxy]carbonyl}phenoxy)decyl] 5-[(11-sulfanylundecanoyl)oxy]benzene-1,3-dicarboxylate